Find out more about our Projects here!
Projects within CAMP are operated within three work packages (WP1-3) covering scientific and technological challenges and infrastructure around process development and production of ATMP.
Twelve collaboration projects engaging partners from healthcare, industry and academy have been started within WP1-3. More projects are under planning and expected to start during 2020.
The current project portfolio consists of the following:
WP1 – Process development
Work package leader – Stefan Scheding
1) Label-free sorting of stromal cell preparations for clinical use
2) ATMP for urethra reconstruction with de- and recellularization technique
3) Development of Multilayered Tissue-Engineered Skin Construct
4) GMP production of pluripotent stem cells and its derivatives.
5) Development of producer lines for delivering therapeutic mRNAs through Extracellular Vesicles.
6) CAR-T cell therapy for malignant melanoma of the skin and the eye.
7) Value survey – How do donors, patients, the general public and policy makers want to balance different interests?
8) Extracellular vesicles (CARMEV) for prevention of heart failure.
WP2 – Infrastructure for GMP manufacturing
Work package leader – Pontus Blomberg
9) Developing a Pre-GMP facility for vectors and genetically modified cells
10) Vecura – An Infrastructure for Development and Manufacturing of ATMPs
11) Expansion of GMP Compliant – Tumor Infiltrating Lymphocytes (TILs) in Xuri bioreactor
12) Harmonizing HQ plasmid production between pre-GMP and GMP sites
13) GMP-compliant infrastructure and production in a hospital-setting of mesenchymal stromal cells from lipoaspirate for use in clinical trials
WP3 – Quality control, shelf-life and logistics
Work package leader – Jim Lund
14) Establishing a QC and logistics strategy of cell-based products for secure patient treatment
15) Single cell qPCR characterization of ATMP
16) Establishing a non-dry ice dependent logistics strategy for cell therapies.