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cytoplasmatisk hybrid

cytoplasmic hybrid embryo (cybrid) [ENGLISH]

Admixed embryo produced by the insertion of human cell or nuclear DNA into an enucleated animal egg or animal-derived cell.

cytoplasmatisk hybrid [SWEDISH]

En cell som skapats genom att en cellkärna från t.ex. en hudcell förts in i ett ägg som tömts på sin egen kärna. Denna cell kommer, utöver kärn-DNA från givaren av cellkärnan, att innehålla mitokondrier (energifabrikerna i cellplasman) och därmed mitokondrie-DNA från båda givarna. Det går att få en sådan cell att börja dela sig som om det vore ett befruktat ägg och bilda ett pre-embryo.

2024-01-29

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Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary https://www.asgct.org/education/more-resources/glossary
  2. 2. Clinical Trials Information System https://www.ema.europa.eu/en/human-regulatory-overview/research-and-development/clinical-trials-human-medicines/clinical-trials-information-system
  3. 3. EMA Glossary of Regulatory Terms https://www.ema.europa.eu/en/about-us/glossaries/glossary-regulatory-terms
  4. 4. EMA Medical Terms simplifier https://www.ema.europa.eu/en/documents/other/ema-medical-terms-simplifier_en.pdf
  5. 5. Glossary of Terms used in EU Clinical Trials Register https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
  6. 6. Glossary of Terms U.S Food and Drug Administration https://www.fda.gov/patients/clinical-trials-what-patients-need-know/glossary-terms
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms” https://www.genome.gov/genetics-glossary/m#glossary
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary https://toolkit.ncats.nih.gov/glossary-2/

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