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T lymfocyt (T cell)

T lymphocyte (T cell) [ENGLISH]

White blood cell of the adaptive part of the body's immune system. Immune cell of lymphatic lineage. Most T cells are αβ (alpha beta) T cells with TCR composed of two glycoprotein chains called α (alpha) and β (beta) TCR chains (with exception of γδ T cells that have a TCR that is made up of one γ (gamma) chain and one δ (delta) chain.) see also T helper cell, cytotoxic T cell, T regulatory cell, gammadelta T cell, NKT cell.

T lymfocyt (T cell) [SWEDISH]

Vit blodkropp som utgör en del av den adaptiva delen av kroppens immunförsvar (se även T-hjälparcell, cytotoxisk T cell, T regulatorisk cell, gammadelta T cell, NKT cell). Uttryck av ytproteiner (cluster of differentiation = CD) används för att definiera typ av T cell och deras funktion. Deras funktion är till viss del adaptiv, exempelvis kan en CD4+ T-hjälparcell eller en CD8+ T cell bli en T regulatorisk cell i en specifik mikromiljö.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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