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T lymfocyt (T cell)

T lymphocyte (T cell) [ENGLISH]

White blood cell of the adaptive part of the body's immune system. Immune cell of lymphatic lineage. Most T cells are αβ (alpha beta) T cells with TCR composed of two glycoprotein chains called α (alpha) and β (beta) TCR chains (with exception of γδ T cells that have a TCR that is made up of one γ (gamma) chain and one δ (delta) chain.) see also T helper cell, cytotoxic T cell, T regulatory cell, gammadelta T cell, NKT cell.

T lymfocyt (T cell) [SWEDISH]

Vit blodkropp som utgör en del av den adaptiva delen av kroppens immunförsvar (se även T-hjälparcell, cytotoxisk T cell, T regulatorisk cell, gammadelta T cell, NKT cell). Uttryck av ytproteiner (cluster of differentiation = CD) används för att definiera typ av T cell och deras funktion. Deras funktion är till viss del adaptiv, exempelvis kan en CD4+ T-hjälparcell eller en CD8+ T cell bli en T regulatorisk cell i en specifik mikromiljö.

2024-01-29

Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary https://www.asgct.org/education/more-resources/glossary
  2. 2. Clinical Trials Information System https://www.ema.europa.eu/en/human-regulatory-overview/research-and-development/clinical-trials-human-medicines/clinical-trials-information-system
  3. 3. EMA Glossary of Regulatory Terms https://www.ema.europa.eu/en/about-us/glossaries/glossary-regulatory-terms
  4. 4. EMA Medical Terms simplifier https://www.ema.europa.eu/en/documents/other/ema-medical-terms-simplifier_en.pdf
  5. 5. Glossary of Terms used in EU Clinical Trials Register https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
  6. 6. Glossary of Terms U.S Food and Drug Administration https://www.fda.gov/patients/clinical-trials-what-patients-need-know/glossary-terms
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms” https://www.genome.gov/genetics-glossary/m#glossary
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary https://toolkit.ncats.nih.gov/glossary-2/

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