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zinkfingernukleas (ZFN)

zinc finger nuclease [ENGLISH]

Group of synthetic, engineered DNA-binding proteins used in targeted genome editing that bind to and cause double-strand DNA breaks at specific locations in the genome.

zinkfingernukleas [SWEDISH]

En genomredigeringsteknik som bygger på att ett restriktionsenzym (zinkfingernukleas) klipper i DNA-spiralen.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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