CAR NK-cell | ATMP Sweden

CAR NK-cell (CAR-NK cell)

chimeric antigen receptor-natural killer cell [ENGLISH]

Natural killer (NK) cells that have been genetically engineered to express a chimeric antigen receptor (CAR) that recognizes specific tumor antigens, thus conferring the ability of these cells to target and kill tumor cells.

CAR NK-cell [SWEDISH]

Naturliga mördarceller (NK) som har modifierats genetiskt för att uttrycka en chimär antigenreceptor (CAR) som känner igen specifika tumörantigener, vilket ger dessa cellers förmåga att rikta in sig på och döda tumörceller.

2024-01-29

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Resources and references

Definitions have been translated into the Swedish language from the following sources:

1. American Society of Gene and Cell Therapy Glossary https://www.asgct.org/education/more-resources/glossary
2. Clinical Trials Information System https://www.ema.europa.eu/en/human-regulatory-overview/research-and-development/clinical-trials-human-medicines/clinical-trials-information-system
3. EMA Glossary of Regulatory Terms https://www.ema.europa.eu/en/about-us/glossaries/glossary-regulatory-terms
4. EMA Medical Terms simplifier https://www.ema.europa.eu/en/documents/other/ema-medical-terms-simplifier_en.pdf
5. Glossary of Terms used in EU Clinical Trials Register https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
6. Glossary of Terms U.S Food and Drug Administration https://www.fda.gov/patients/clinical-trials-what-patients-need-know/glossary-terms
7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms” https://www.genome.gov/genetics-glossary/m#glossary
8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
9. Toolkit For Patient Focused Therapy Development Glossary https://toolkit.ncats.nih.gov/glossary-2/

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