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cytotoxisk T cell (CTL)

cytotxic T cell [ENGLISH]

A cytotoxic T cell (also known as TC, cytotoxic T lymphocyte, CTL, T-killer cell, cytolytic T cell, CD8+ T-cell or killer T cell) is a T lymphocyte (a type of white blood cell) that kills cancer cells, cells that are infected by intracellular pathogens (such as viruses or bacteria), or cells that are damaged in other ways.

cytotoxisk T cell [SWEDISH]

Cytotoxiska T-celler (CTL) dödar/inducerar apotos virusinfekterade celler och tumörceller, och är också inblandade i avstötning av transplantat. Dessa celler kallas även CD8+ T-celler (associerade med MHC klass I), eftersom de uttrycker CD8 glykoprotein på ytan. Genom interaktion med T-hjälpar-celler kan dessa celler omvandlas till regulatoriska T-celler.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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