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genetisk instabilitet

genetic instability [ENGLISH]

Degradation of genome integrity leading to a high frequency of mutations and diverse genetic modifications.

genetisk instabilitet [SWEDISH]

Det kännetecknas av en arvsmassa i ständig förändring och är ett vanligt fenomen i många cancerformer, i synnerhet bland tumörer med aggressivt förlopp och dålig prognos.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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