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homolog reparation (HDR)

homology-directed repair [ENGLISH]

Mechanism for the precise repair of double-strand breaks in DNA that takes place when a non-broken homologous DNA sequence is present in the nucleus, which is used as a template for DNA repair synthesis that bridges the double-strand break.

homolog reparation [SWEDISH]

Mekanism för exakt reparation av dubbelsträngsbrott i DNA som sker när en obruten homolog DNA-sekvens finns i kärnan, som används som mall för DNA-reparationssyntes som överbryggar dubbelsträngsbrottet.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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