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organ konstruktion

whole-organ engineering [ENGLISH]

Creation of functional replacement organs through the decellularization and subsequent recellularization of allogeneic/xenogeneic donor organs, resulting in a 3D extracellular matrix (ECM) that closely resembles the native tissue architecture and aims to mimic organ-specific functionality.

organ konstruktion [SWEDISH]

Skapande av funktionella ersättningsorgan genom decellularisering och efterföljande recellularisering av allogena/xenogena donatororgan, vilket resulterar i en extracellulär 3D-matris (ECM) som är mycket lik den ursprungliga vävnadsarkitekturen och syftar till att efterlikna organspecifik funktionalitet.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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