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redigering av epigenom

epigenome editing [ENGLISH]

Genetic engineering approach in which the epigenome is modified through the use of mutationally-modified genome-editing toolsets to alter chromatin decoration at precise genomic loci, without altering the underlying DNA sequence.

redigering av epigenom [SWEDISH]

Genteknik där epigenomet modifieras genom användning av mutationsmodifierade genomredigeringsverktyg för att ändra epigenetiska kromatinmodifieringar vid exakta genomiska loci, utan att ändra den underliggande DNA-sekvensen.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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