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RNA-interferens (RNAi)

RNA interference [ENGLISH]

Cellular mechanism in which RNA molecules inhibit the translation step of gene expression by neutralizing specific messenger RNA (mRNA) molecules, used in gene therapy for the silencing of specific genes

RNA-interferens [SWEDISH]

Ett fenomen i levande celler, där dubbelsträngat RNA kan tysta en gen så att den inte uttrycks. Detta kan ses som ett slags immunförsvar för genomet.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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