ATMP - epitelial mesenkymal transition

epitelial mesenkymal transition (EMT)

epithelial–mesenchymal transition [ENGLISH]

process by which epithelial cells undergo multiple biochemical, physiological and morphological alterations to lose their cell polarity and cell–cell adhesion and to acquire the motile and invasive properties of Mesenchymal stem cells (MSCs).

epitelial mesenkymal transition [SWEDISH]

Process i vilken epitelceller genomgår flera biokemiska, fysiologiska och morfologiska förändringar för att förlora sin cellpolaritet och cell-celladhesion och för att förvärva de rörliga och invasiva egenskaperna hos mesenkymala stamceller (MSCs).

2024-01-29

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Resources and references

Definitions have been translated into the Swedish language from the following sources:

1. American Society of Gene and Cell Therapy Glossary https://www.asgct.org/education/more-resources/glossary
2. Clinical Trials Information System https://www.ema.europa.eu/en/human-regulatory-overview/research-and-development/clinical-trials-human-medicines/clinical-trials-information-system
3. EMA Glossary of Regulatory Terms https://www.ema.europa.eu/en/about-us/glossaries/glossary-regulatory-terms
4. EMA Medical Terms simplifier https://www.ema.europa.eu/en/documents/other/ema-medical-terms-simplifier_en.pdf
5. Glossary of Terms used in EU Clinical Trials Register https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
6. Glossary of Terms U.S Food and Drug Administration https://www.fda.gov/patients/clinical-trials-what-patients-need-know/glossary-terms
7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms” https://www.genome.gov/genetics-glossary/m#glossary
8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
9. Toolkit For Patient Focused Therapy Development Glossary https://toolkit.ncats.nih.gov/glossary-2/

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