ATMP - onkogen

onkogen

oncogene [ENGLISH]

A gene that is associated with cancer. When a gene that regulates growth under normal conditions develops mutations that contribute to a cell becoming cancerous, the mutated gene is called an oncogene. Certain viruses can also carry oncogenes. Oncogenes play a key role in the transformation of normal cells into cancer cells.

onkogen [SWEDISH]

Cancerframkallande. Kan också betyda cancergen, som är ett arvsanlag som gör så att en normal cell kan omvandlas till en cancercell. Onkogener är från början normala gener som har genomgått en liten förändring. Onkogener är ofta involverade i celldelning, eller liknande processer.

2024-01-29

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Resources and references

Definitions have been translated into the Swedish language from the following sources:

1. American Society of Gene and Cell Therapy Glossary https://www.asgct.org/education/more-resources/glossary
2. Clinical Trials Information System https://www.ema.europa.eu/en/human-regulatory-overview/research-and-development/clinical-trials-human-medicines/clinical-trials-information-system
3. EMA Glossary of Regulatory Terms https://www.ema.europa.eu/en/about-us/glossaries/glossary-regulatory-terms
4. EMA Medical Terms simplifier https://www.ema.europa.eu/en/documents/other/ema-medical-terms-simplifier_en.pdf
5. Glossary of Terms used in EU Clinical Trials Register https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
6. Glossary of Terms U.S Food and Drug Administration https://www.fda.gov/patients/clinical-trials-what-patients-need-know/glossary-terms
7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms” https://www.genome.gov/genetics-glossary/m#glossary
8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
9. Toolkit For Patient Focused Therapy Development Glossary https://toolkit.ncats.nih.gov/glossary-2/

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