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polymorfism, restriktionsfragmentlängd (RFLP)

restriction fragment length polymorphism [ENGLISH]

A type of polymorphism that results from variation in the DNA sequence recognized by restriction enzymes which are bacterial enzymes used by scientists to cut DNA molecules at known locations.

polymorfism, restriktionsfragmentlängd [SWEDISH]

En typ av polymorfism som beror på variation i den DNA-sekvens som identifieras av restriktionsendonukleaser. (De kan känna igen specifika sekvenser av DNA och där kapa dem till DNA-fragment i en specifik storlek). Det används för genetisk typning, en metod som används för att skapa DNA-profiler oftast i samband med kriminologi.

2024-01-29

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Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary https://www.asgct.org/education/more-resources/glossary
  2. 2. Clinical Trials Information System https://www.ema.europa.eu/en/human-regulatory-overview/research-and-development/clinical-trials-human-medicines/clinical-trials-information-system
  3. 3. EMA Glossary of Regulatory Terms https://www.ema.europa.eu/en/about-us/glossaries/glossary-regulatory-terms
  4. 4. EMA Medical Terms simplifier https://www.ema.europa.eu/en/documents/other/ema-medical-terms-simplifier_en.pdf
  5. 5. Glossary of Terms used in EU Clinical Trials Register https://www.clinicaltrialsregister.eu/doc/EU_Clinical_Trials_Register_Glossary.pdf
  6. 6. Glossary of Terms U.S Food and Drug Administration https://www.fda.gov/patients/clinical-trials-what-patients-need-know/glossary-terms
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms” https://www.genome.gov/genetics-glossary/m#glossary
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary https://toolkit.ncats.nih.gov/glossary-2/

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