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base editing [ENGLISH]

Genome-editing approach that introduces precise point mutations (conversion of one target base/base pair into another) in genomic DNA or RNA without the need to induce a double-strand break, unlike most other genome-editing techniques, thereby minimizing the formation of undesired genomic byproducts.

basparsredigering [SWEDISH]

Grupp av studiedeltagare som kännetecknas av den intervention eller behandlingsregim de får i en klinisk prövning.


Resources and references

Definitions have been translated into the Swedish language from the following sources:

  1. 1. American Society of Gene and Cell Therapy Glossary
  2. 2. Clinical Trials Information System
  3. 3. EMA Glossary of Regulatory Terms
  4. 4. EMA Medical Terms simplifier
  5. 5. Glossary of Terms used in EU Clinical Trials Register
  6. 6. Glossary of Terms U.S Food and Drug Administration
  7. 7. National Human Genome Research Institute “Talking Glossary of Genomic and Genetic Terms”
  8. 8. The Glossary for Advanced Therapies Regen. Med. Dec 2020 Vol. 15 No. 12 Suppl. 1
  9. 9. Toolkit For Patient Focused Therapy Development Glossary

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